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CBD (Cannabidiol) is one of many chemical compounds produced by cannabis. CBD oil refers to an extract of cannabis or hemp that is formulated to contain high CBD levels and may include various amounts of other plant compounds.
Products that contain only CBD have a non-psychoactive effect, unlike THC products, meaning you don’t provide the many high associated with cannabis.
When it comes to choosing a form of CBD, things can get pretty confusing, but we’re here to help!
The following products are some of the most popular forms of CBD:
– CBD Topicals: CBD topicals penetrate the skin to provide targeted relief without entering the bloodstream.
– CBD Tinctures/Additives: CBD Tinctures/Additives are products that are liquid extracts that are applied under the tongue, added to coffees/ or teas, or infused in any recipe you desire!
– CBD Vapeables: CBD Vapeables are designed to be added to any currently available vaping e-liquid!

Products that contain only CBD have a non-psychoactive effect, unlike THC products, meaning you don’t get high.

When it comes to CBD, there are three main types: Full Spectrum, Broad Spectrum, and Isolate
– Full Spectrum: Contains all of the plant compounds, including THC
– Broad Spectrum: Contains all of the plant compounds minus the THC
– Isolate: Contains only CBD. All other compounds have been removed

How does CBD work in your body?
The Endocannabinoid (pictured) system is a cell-signaling system in our bodies. So far, we know that the ECS (Endocannabinoid System) help with the regulation of the following functions:
– Sleep
– Mood
– Appetite
– Memory
The ECS exists in your body, even if you don’t use cannabis!

How does the Endocannabinoid system work? (pictured)
The ECS reacts with receptors, and there are two main kinds.
– CB1 Receptors: mostly found in the central nervous system
– CB2 Receptors: mostly found in the peripheral nervous system

CBD popularity can be on the rise, and it’s in part due to the nature of CBD and the range of consumption methods available. Edibles and tinctures can have less of the stigma traditionally associated with joints. 

When our products are taken orally, bioavailability can become compromised. 

This doesn’t signify a lesser product; in fact, our CBD oil is among the most effective on the market. What we are referring to is just the way oil works with the human body. 

Want to get the most out of them? Here are our suggestions. 

Like THC oils, CBD resists absorption into the bloodstream because the human body is up to 60% water. Mixing oil and water is no easy task. It’s just basic science.

That same concept can be analogous to the way cannabinoids work in the body. 

CBD and its family of compounds are fat-loving molecules and have to in aqueous cellular pathways. Which makes sense when you consider just how much of the human body is comprised of water. 

So the idea is that when cannabis is consumed as an oil, the onset of effects can become delayed and bioavailability limited.

This is contrary to the idea that the oil, often coconut oil being the medium, is the correct dosing method. 

Proper Dosing With CBD Oil

Dosage is the critical factor in achieving the most benefits and least adverse effects of cannabis. 

Considering bioavailability, these are the measurements recommended:

• Appetite: 2.5 milligrams of THC by mouth with or without 1 mg of CBD for six weeks
• Chronic pain: 2.5-20 mg CBD by mouth for an average of 25 days  
• Sleep disorders: 40-160 mg CBD by mouth.  

CannLabs, the nation’s top full-service testing lab for cannabis products, has determined no regular lethal CBD dose. Consumers should read product inserts carefully to ensure they are taking the right amount of CBD and talk to their prescribing physician about any questions or concerns.

The First-Pass Effect

The first-pass effect is what limits oil-based cannabis extracts from reaching the bloodstream in large quantities. Orally, CBD is absorbed in the gastrointestinal tract and transported via the portal vein to the liver, where metabolized and made of use to the body.

Since cannabis oil is often taken orally, its efficacy can be hindered.

Are some cannabinoids more bioavailable than others?

Investigations into CBD have shown that the bioavailability of cannabinoids depends on the method of delivery. 

How to Optimize Bioavailability?

Since the CBD market explosion, a slew of products has rushed onto the market. However, they might be the culprit in limiting bioavailability. The “first pass” through the liver is the mechanism we want to understand. With oral CBD, absorption can be slow, unpredictable, and highly variable.

Despite the absorption speed, oral administration lasts longer than smoking, eliminating the need for frequent dosing. Oral and topical methods also avoid irritation to the airways and the risk of malignancies associated with smoking or vaping.

By following dosage guidelines and understanding limited bioavailability via consumption methods, we hope you can make the most of all your CBD products. 

CBD works differently for everyone; here’s our recommendation: use the full dropper once in the morning and increase dosage if needed. Make sure to keep track of your dosage and see how you feel over time.

You’ve bought a tincture from another company or us; you’re in observation mode. This means being careful to read lab results, understand them, and record your routine.

Here’s our guide to CBD dosing and techniques:

Trying to notice if you feel different, and looking for signs that the product is working.

That’s very normal with any supplement medication or change to your diet.

The advent of hemp-derived oil concentrates, non-intoxicating cannabidiol products, and innovative, smokeless delivery systems have transformed the therapeutic landscape. The national conversation about cannabinoids has entirely changed over the last few years.

Dosage and Beginners

Cannabidiol comes in various forms with a wide range of potencies, and its production and distribution have yet to become standardized. The goal is to take a broad enough dose to achieve therapeutic results and a small enough quantity to reduce adverse side effects.

Contrary to popular belief, ultra-low doses can be beneficial, and this comes at a low price-point.

The jury is out when it comes to scientific evidence that CBD does anything.

Concentrated oil extracts, tinctures, edibles, pre-rolls, loose-leaf hemp, and other products all make it easy to get some of these compounds, CBD, and terpenes, into your system.

If you’re getting relief from the dosage, then you’re in the Goldilocks zone. But if you’re feeling too tired or experiencing diarrhea, then the dosage should be lowered. The practice revolves around keeping track of how much you’re consuming. Starting small and working from there.

Cannabidiol (CBD) does not cause an intoxicating high like THC.

CBD can lessen or neutralize the THC high, depending on how much each compound is present in a particular product. 1,500 mg/day of CBD is reportedly well tolerated in humans, so it’s not a toxic substance in the slightest. Still, everyone is different. Just remember:

Beginning CBD Dosage

The adage “start low and go slow” is apropos for Cannabidiol therapy.

As for oral administration, one should keep in mind that it can take 60 to 90 minutes before the effects of a single dose can be noticed.

The use of ingestible CBD-rich products can be taken anytime. It’s recommended to use it with breakfast or dinner, or shortly before bedtime. Continue use, and monitor dosage until the desired effects are achieved.

If there are adverse side effects, reduce the dose to the prior amount.

Some patients may need to ingest their CBD two or three times during daylight hours and their night-time regimen for adequate symptom relief.

Cautious titration is urged: On days 1 and 2, start with one dose.
On days 3 and 4, increase the dosage to twice a day; and, if well tolerated, increase the dose incrementally.

Doses exceeding the average may increase adverse events or induce tolerance without improving efficacy.

Adverse events are dose-dependent. Very high doses are more likely to cause unwanted side effects.

For most medications, a higher dose will pack a more potent therapeutic punch. However, endocannabinoids have biphasic properties, meaning that low and high doses generate opposite effects. Small quantities tend to stimulate; large doses sedate.

It is important to note that every person on the planet responds differently and builds tolerance at different rates.

By introducing small amounts of CBD into your system and increasing the dosage slowly, you minimize adverse side effects.

CBD is a safe and forgiving medicine, but talking with your physician is a must.

Uncle Funky is always around to answer your questions. We’ve dedicated the farm to growing hemp to help people and offer a product we believe in.